World’s biggest killer: Hyperinsulinaemia.

In an excellent report about hyperinsulinaemia/Insulin resistance by Michael Joseph MSc the following valuable information become available;

Full article:

Hyperinsulinaemia refers to when the body is producing to much insulin to keep high blood sugar levels in check. Without adequate intervention chronic hyperinsulinaemia can lead to type 2 Diabetes.

But hyperinsulinaemia is associated with the metabolic syndrome and is harmful independent of Diabetes.

What causes insulin resistance, hyperinsulinaemia and metabolic syndrome; there are several factors but most of all our modern diet with refines sugars and ultraprocessed foods with too much carbohydrates.

Link between Hyperinsulinaemia and Chronic disease.

Alzheimer: Hyperinsulinaemia has a robust association with a higher risk of Alzheimer’s disease. Ref: 150980

Cancer: Individuals with high levels of insulin have a 62% higher risk of cancer mortality. Chronic Hyperinsulinaemia may raise cancer risk by increasing the bioligical activity of IGF-1 which can help tumor growth. Insulin can also directly influence tumor growth.

Cardiovascular disease:

Hyperinsulinaemia stimulates production of proinflammatory cytokines in vascular systems and endothelial cells promoting premature atherosclerosis.

Chronic kidney disease:

Hyperinsulinaemia can lead to CKD through oxidative stress, stimulating growth factors and downregulating renal receptors.


Key Point: Hyperinsulinaemia appears to play a pivotal role in the pathology of major chronic diseases. 

How can we reverse insulin resistance?

Low carbohydrate diets.


Intermittent fasting.

Good sleep.

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